Growth Hormone Secretagogues & GHRH
Anterior Pituitary Somatotroph Receptors & Pulsatile Endocrine Cascades
Analytical biochemical profiles for synthetic growth hormone secretagogue receptor (GHSR-1a) agonists and growth hormone-releasing hormone (GHRH) analogues evaluated for selective pituitary signaling and downstream IGF-1 transcription.
Reagents in this Signaling Category
CJC-1295
Modified Growth Hormone-Releasing Hormone (Mod GRF 1-29 / CJC-1295 No DAC)
CJC-1295 (Mod GRF 1-29) is a synthetic 29-amino-acid analogue of human growth hormone-releasing factor featuring four D-amino acid substitutions to enhance metabolic stability against dipeptidyl peptidase-4 (DPP-4). Evaluated in UK endocrine research for pulsatile somatotroph signaling.
Ipamorelin
Aib-His-D-2-Nal-D-Phe-Lys-NH2 Pentapeptide
Ipamorelin is a synthetic pentapeptide and selective ghrelin receptor (GHSR-1a) agonist. Distinct from earlier GHRPs due to its selectivity: it stimulates somatotroph growth hormone release in vitro without triggering substantial elevation in cortisol, prolactin, or ACTH.